Prof. Dr. Rebekka LencerInstitute for Translational PsychiatryAlbert-Schweitzer-Campus 1 D - 48149 Münster Phone: +49 (0)251 / 83-52581 Fax: +49 (0)251 / 83-57128 Email: lencer@uni-muenster.de |
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Research Areas
- Neurocognition and sensorimotor processing in psychosis
- Neuropsychiatric disorders in (genetically determined) movement disorder
- Cortical networks for oculomotor function
- Defining neurophysiological intermediate phenotypes for genetic analyses
Fig.1-3: Visual exploration of daily live scenes
Selected Publications
Lencer R, Mills LJ, Alliey-Rodriguez N; Shafee R, Lee A, Reilly JL, Sprenger A, McDowell JE, McCarroll SA, Keshavan MS, Pearlson GD, Tamminga CA,Clementz BA, Gershon ES, Sweeney JA, Bishop JR (2017). Genome-wide association studies of smooth pursuit and antisaccade eye movements in psychotic disorders: findings from the B-SNIP study. Translational Psychiatry 7, e1249; doi:10.1038/tp.2017.210
Lencer R, Meermeier A, Silling K, Gremmler S, Lappe M (2017) Instability of visual error processing for sensorimotor adaptation in schizophrenia. European Archives of Psychiatry and Clinical Neuroscience 267(3):237-244.
Trillenberg P, Sprenger A, Talamo S, Herold K, Helmchen C, Verleger R, Lencer R (2017) Visual and non-visual motion information processing during pursuit eye tracking in schizophrenia and bipolar disorder. European Archives of Psychiatry and Clinical Neuroscience 267(3):225-235.
Lencer R, Sprenger A, Reilly JL, McDowelld JE, Rubin LH, Badner JA, Keshavan MS, Pearlson GD, Tamminga CA, Gershon ES, Clementz BA, Sweeney JA (2015) Pursuit eye movements as an intermediate phenotype across psychotic disorders: evidence from the B-SNIP study. Schizophrenia Research, 169(1-3): 326-333.
Lencer R, Nagel M, Sprenger A, Zapf S, Erdmann C, Heide W, Binkofski F (2004) Cortical mechanisms of smooth pursuit eye movements with target blanking. An fMRI study. European Journal of Neuroscience, 19 (5):1430-6.
Academic CV
| 1984-1990 | Studies of human medicine and romanistic at the Universities in Bochum and Berlin, stay abroad in Cadiz, Spain |
| 1990 | Medical state examination |
| 1993 | Promotion |
| 1994 | Full approbation |
| 1993–1998 | Member of the research group „Molecular genetic and phenotypic markers in families with multiple occurrence of psychosis“ and „Oculomotor performance and schizophrenia“, Leadership: Prof. V. Arolt, Prof. E. Schwinger, Prof. W. Heide, Lübeck |
| 1993-2000 | Assistent doctor at the department of Psychiatry und Psychotherapy, University of Lübeck |
| 1998–1999 | Assistent doctor at the department of Neurology, University of Lübeck |
| 1999 | Medical specialist for Psychiatry und Psychotherapy |
| since 1999 | Leader of the research group „Neurobiology of psychotic disorders“ |
| 2001 | Senior physician at the department of Psychiatry und Psychotherapy, University of Lübeck |
| 2007-2009 | Research Fellow at the Center for Cognitive Medicine, University of Illinois at Chicago, USA |
| 2010 | Professor of Psychiatry and Psychotherapy, University of Lübeck |
| 2010 | Leader of the research group “Perception and Action in Psychiatric Disorders”, University of Münster |
| since 2010 | Vice chair of the department of Psychiatry and Psychotherapy, University of Münster |
| 2014 | Professor of Psychiatry and Psychotherapy, University of Münster |
| since 2014 | Speaker of the Otto Creutzfeldt Center for Cognitive and Behavioral Neuroscience, WWU Münster |
| 2018 | Visiting professor Institute of Social Sciences and Psychology, Western Sydney University, Australia (5 weeks) |
Honours and Special Recognitions
| 1998 | Young Scientist Award (Winter Workshop on Schizophrenia (Prof. Stephen Hirsch, Prof. Timothy Crow, London) |
| 2002, 2006 | Senior Scientist Award (Winter Workshop on Schizophrenia (Prof. Stephen Hirsch, Prof. Timothy Crow, London) |
Research Database CRIS@WWU
Projects
- DFG Schizo – Multi-channel transcranial direct current stimulation (mc-tDCS):a novel approach to modulate smooth pursuit eye movement control in healthy individuals and patients with psychotic disorders ( – )
Own resources project - mPIVAS – mHealth psychoeducational intervention versus antipsychotic-induced effects ( – )
EU-project hosted outside University of Münster: EC - Lifelong Learning Programme: Leonardo da Vinci | Project Number: 2013-1-HR1-LEO04-032256
- DFG Schizo – Multi-channel transcranial direct current stimulation (mc-tDCS):a novel approach to modulate smooth pursuit eye movement control in healthy individuals and patients with psychotic disorders ( – )
Publications
- . . ‘Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium.’ Proceedings of the National Academy of Sciences of the United States of America (PNAS) 120, No. 14: e2213880120. doi: 10.1073/pnas.2213880120.
- . . ‘Large-scale analysis of structural brain asymmetries in schizophrenia via the ENIGMA consortium.’ Proceedings of the National Academy of Sciences of the United States of America (PNAS) 120, No. 14: e2213880120. doi: 10.1073/pnas.2213880120.
- . . ‘The impact of visual dysfunctions in recent-onset psychosis and clinical high-risk state for psychosis.’ Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 47, No. 12: 2051–2060. doi: 10.1038/s41386-022-01385-3.
- . . ‘Effects of DRD2/ANKK1 and COMT Val158Met polymorphisms on stabilization against and adaptation to unexpected vents.’ Cerebral cortex 00, 1–18. doi: 10.1093/cercor/bhac046.
- . . ‘Subtyping Schizophrenia Patients Based on Patterns of Structural Brain Alteration .’ Schizophrenia Bulletin 48. doi: 10.1093/schbul/sbab110.
- . . ‘Clinical, Brain, and Multilevel Clustering in Early Psychosis and Affective Stages.’ JAMA Psychiatry 79: 677–689. doi: 10.1001/jamapsychiatry.2022.1163.
- . . ‘Deficits in generalized cognitive ability, visual sensorimotor function, and inhibitory control represent discrete domains of neurobehavioral deficit in psychotic disorders.’ Schizophrenia Research 236. doi: 10.1016/j.schres.2021.07.036.
- . . ‘Cerebral and behavioral signs of impaired cognitive flexibility and stability in schizophrenia spectrum disorders .’ NeuroImage: Clinical 32. doi: 10.1016/j.nicl.2021.102855.
- . . ‘Cognitive subtypes in recent onset psychosis: distinct neurobiological fingerprints? .’ Neuropsychopharmacology 46: 1475–1483. doi: 10.1038/s41386-021-00963-1.
- . . ‘Multimodal Machine Learning Workflows for Prediction of Psychosis in Patients With Clinical High-Risk Syndromes and Recent-Onset Depression.’ JAMA Psychiatry 78. doi: 10.1001/jamapsychiatry.2020.3604.
- . . ‘Traces of Trauma: A Multivariate Pattern Analysis of Childhood Trauma, Brain Structure, and Clinical Phenotypes .’ Biological Psychiatry 88. doi: 10.1016/j.biopsych.2020.05.020.
- . ‘Effective assessment of psychotropic medication side effects using PsyLOG mobile application.’ Schizophrenia Research null, No. null. doi: 10.1016/j.schres.2017.04.038. [online first]
- . . ‘Instability of visual error processing for sensorimotor adaptation in schizophrenia.’ European Archives of Psychiatry and Clinical Neuroscience 2016.
- . ‘The psylog mobile application: Development of a tool for the assessment and monitoring of side effects of psychotropic medication.’ Psychiatria Danubina 29, No. 2: 214–217.
- . ‘Specificity and sensitivity of visual evoked potentials in the diagnosis of schizophrenia: Rethinking VEPs.’ Schizophrenia Research 2015, No. 166: 231–234. doi: 10.1016/j.schres.2015.05.007.
- . . ‘Social alienation in schizophrenia patients: Association with insula responsiveness to facial expressions of disgust.’ PloS one 9, No. 1. doi: 10.1371/journal.pone.0085014.
- . . ‘Automatic amygdala response to facial expression in schizophrenia: Initial hyperresponsivity followed by hyporesponsivity. .’ BMC Neuroscience 14. doi: 10.1186/1471-2202-14-140.
Promotion
Surmann, Marian Wie kann die Behandlung von Betroffenen mit psychotischen Erkrankungen verbessert werden? Eine Verschiebung des Behandlungsfokus jenseits der Pharmakotherapie. Marian Surmann Wie kann die Behandlung von Betroffenen mit psychotischen Erkrankungen verbessert werden? Eine Verschiebung des Behandlungsfokus jenseits Pharmakotherapie. Trempler, Ima Carolyn Neurocognitive Mechanisms of Flexibility and Stability of Prediction and their lmpairment in Parkinson's Disease